The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment

The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment

The palmitoyl acyltransferase (PAT) ZDHHC14 is highly expressed in the hippocampus and is the only PAT predicted to bind Type-I PDZ domain-containing proteins. However, ZDHHC14’s neuronal roles are unknown. Here, we identify the PDZ domain-containing Membrane-associated Guanylate Kinase (MaGUK) PSD9...

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Bibliographic Details
Main Authors: Shaun S Sanders, Luiselys M Hernandez, Heun Soh, Santi Karnam, Randall S Walikonis, Anastasios V Tzingounis, Gareth M Thomas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
palmitoylation
PSD93
voltage-gated potassium channels
ZDHHC14
DLG2
Kv1 channels
Online Access:https://elifesciences.org/articles/56058

Internet

https://elifesciences.org/articles/56058

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