Nicotinic receptor β2 determines NK cell-dependent metastasis in a murine model of metastatic lung cancer.

Cigarette smoke exposure markedly compromises the ability of the immune system to protect against invading pathogens and tumorigenesis. Nicotine is a psychoactive component of tobacco products that acts as does the natural neurotransmitter, acetylcholine, on nicotinic receptors (nAChRs). Here we dem...

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Bibliographic Details
Main Authors: Junwei Hao, Fu-Dong Shi, Mohammed Abdelwahab, Samuel X Shi, Alain Simard, Paul Whiteaker, Ronald Lukas, Qinghua Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585320?pdf=render