Spatial profiling of METex14-altered NSCLC under tepotinib treatment: Shifting the immunosuppressive landscape

Spatial profiling of METex14-altered NSCLC under tepotinib treatment: Shifting the immunosuppressive landscape

MET inhibitors have demonstrated efficacy in treating patients with non-small cell lung cancer (NSCLC) harboring METex14 skipping alterations. Advancements in spatial profiling technologies have unveiled the complex dynamics of the tumor microenvironment (TME), a crucial factor in cancer progression...

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Bibliographic Details
Main Authors: Manon A Simard, Carlos Cabrera-Galvez, Santiago Viteri, Felix Geist, Nadine Reischmann, Michael Zühlsdorf, Niki Karachaliou
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Tepotinib
Spatial profiling
GeoMx
NSCLC
METex14
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558624001040

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http://www.sciencedirect.com/science/article/pii/S1476558624001040

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