Transcriptomic analysis reveals a tissue-specific loss of identity during ageing and cancer

Abstract Introduction Understanding changes in cell identity in cancer and ageing is of great importance. In this work, we analyzed how gene expression changes in human tissues are associated with tissue specificity during cancer and ageing using transcriptome data from TCGA and GTEx. Results We fou...

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Bibliographic Details
Main Authors: Gabriel Arantes dos Santos, Kasit Chatsirisupachai, Roberto A. Avelar, João Pedro de Magalhães
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09756-w