Fueling the flames of colon cancer – does CRP play a direct pro-inflammatory role?

Fueling the flames of colon cancer – does CRP play a direct pro-inflammatory role?

BackgroundSystemic inflammation, diagnostically ascribed by measuring serum levels of the acute phase reactant C-reactive protein (CRP), has consistently been correlated with poor outcomes across cancer types. CRP exists in two structurally and functionally distinct isoforms, circulating pentameric...

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Bibliographic Details
Main Authors: Anne Helene Køstner, Anniken Jørlo Fuglestad, Jeanette Baehr Georgsen, Patricia Switten Nielsen, Kristina Bang Christensen, Helle Zibrandtsen, Erik Thorlund Parner, Ibraheem M. Rajab, Lawrence A. Potempa, Torben Steiniche, Christian Kersten
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
systemic inflammation
C-reactive protein (CRP)
CRP isoforms
monomeric CRP
colon cancer
immunohistochemistry (IHC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1170443/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1170443/full

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