P10.05 REDUCED MOLECULAR FLEXIBILITY IN THE LARGE ARTERIES OF DIABETIC RATS

In Type 1 and 2 diabetes tissue stiffening is evident from measurements of the gross mechanical properties of the vasculature. In general, pathological glycosylation of extracellular matrix proteins may play an important role in increasing stiffness in diabetic patients. However, the effects of diab...

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Bibliographic Details
Main Authors: R. Akhtar, N. Gardiner, J.K. Cruickshank, B. Derby, M.J. Sherratt
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125927233/view