New perspectives on an old grouping: The genomic and phenotypic variability of Oxalobacter formigenes and the implications for calcium oxalate stone prevention

New perspectives on an old grouping: The genomic and phenotypic variability of Oxalobacter formigenes and the implications for calcium oxalate stone prevention

Oxalobacter formigenes is a unique bacterium with the ability to metabolize oxalate as a primary carbon source. Most kidney stones in humans are composed of calcium and oxalate. Therefore, supplementation with an oxalate-degrading bacterium may reduce stone burden in patients suffering from recurren...

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Bibliographic Details
Main Authors: John A. Chmiel, Charles Carr, Gerrit A. Stuivenberg, Robertson Venema, Ryan M. Chanyi, Kait F. Al, Daniel Giguere, Henry Say, Polycronis P. Akouris, Sergio Ari Domínguez Romero, Aaron Kwong, Vera Tai, Susan F. Koval, Hassan Razvi, Jennifer Bjazevic, Jeremy P. Burton
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
oxalate degradation
Oxalobacter formigenes
kidney stone disease
gut microbiome
revised taxonomy
phylogenomic and comparative genomic analyses
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1011102/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1011102/full

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