Age-related elevation of O-GlcNAc causes meiotic arrest in male mice
Abstract In recent years, the postponement of childbearing has become a critical social issue. Male fertility is negatively associated with age because of testis aging. Spermatogenesis is impaired with age, but the molecular mechanism remains unknown. The dynamic posttranslational modification O-lin...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-05-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01433-x |