Directly injected lentiviral vector–based T cell vaccine protects mice against acute and chronic viral infection

Lentiviral vector–based dendritic cell vaccines induce protective T cell responses against viral infection and cancer in animal models. In this study, we tested whether preventative and therapeutic vaccination could be achieved by direct injection of antigen-expressing lentiviral vector, obviating t...

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Bibliographic Details
Main Authors: Takuya Tada, Thomas D. Norton, Rebecca Leibowitz, Nathaniel R. Landau
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-09-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.161598