Directly injected lentiviral vector–based T cell vaccine protects mice against acute and chronic viral infection
Lentiviral vector–based dendritic cell vaccines induce protective T cell responses against viral infection and cancer in animal models. In this study, we tested whether preventative and therapeutic vaccination could be achieved by direct injection of antigen-expressing lentiviral vector, obviating t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-09-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.161598 |