Reversing the Natural Drug Resistance of Gram-Negative Bacteria to Fusidic Acid via Forming Drug–Phospholipid Complex

Reversing the Natural Drug Resistance of Gram-Negative Bacteria to Fusidic Acid via Forming Drug–Phospholipid Complex

Drug resistance substantially compromises antibiotic therapy and poses a serious threat to public health. Fusidic acid (FA) is commonly used to treat staphylococcal infections, such as pneumonia, osteomyelitis and skin infections. However, Gram-negative bacteria have natural resistance to FA, which...

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Bibliographic Details
Main Authors: Jianhong Liu, Xuyang Lai, Yuanhong Li, Zhuohang Yu, Xuan Wang, Chaoliang Zhang, Qiang Peng
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Bioengineering
Subjects:
drug delivery
drug resistant
phospholipid complex
antimicrobial
antibiotics
Online Access:https://www.mdpi.com/2306-5354/11/2/177

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https://www.mdpi.com/2306-5354/11/2/177

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