A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.

The C-terminus of the voltage-gated calcium channel Cav1.2 encodes a transcription factor, the calcium channel associated transcriptional regulator (CCAT), that regulates neurite extension and inhibits Cav1.2 expression. The mechanisms by which CCAT is generated in neurons and myocytes are poorly un...

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Bibliographic Details
Main Authors: Natalia Gomez-Ospina, Georgia Panagiotakos, Thomas Portmann, Sergiu P Pasca, Dania Rabah, Agata Budzillo, Jean Pierre Kinet, Ricardo E Dolmetsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3628902?pdf=render