Improved interpretation of 18F-florzolotau PET in progressive supranuclear palsy using a normalization-free deep-learning classifier

Summary: While 18F-florzolotau tau PET is an emerging biomarker for progressive supranuclear palsy (PSP), its interpretation has been hindered by a lack of consensus on visual reading and potential biases in conventional semi-quantitative analysis. As clinical manifestations and regions of elevated...

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Bibliographic Details
Main Authors: Jiaying Lu, Christoph Clement, Jimin Hong, Min Wang, Xinyi Li, Lara Cavinato, Tzu-Chen Yen, Fangyang Jiao, Ping Wu, Jianjun Wu, Jingjie Ge, Yimin Sun, Matthias Brendel, Leonor Lopes, Axel Rominger, Jian Wang, Fengtao Liu, Chuantao Zuo, Yihui Guan, Qianhua Zhao, Kuangyu Shi
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223015031