Plasma Levels of α-Synuclein, Aβ-40 and T-tau as Biomarkers to Predict Cognitive Impairment in Parkinson’s Disease

Plasma Levels of α-Synuclein, Aβ-40 and T-tau as Biomarkers to Predict Cognitive Impairment in Parkinson’s Disease

ObjectiveIn this study, we assessed plasma biomarkers to identify cognitive impairment in Parkinson’s disease (PD) patients by applying ultra-sensitive immunomagnetic reduction-based immunoassay (IMR).MethodsThe study enrolled 60 PD patients and 28 age- and sex-matched normal controls. Complete cogn...

Full description

Bibliographic Details
Main Authors: Nai-Ching Chen, Hsiu-Ling Chen, Shau-Hsuan Li, Yen-Hsiang Chang, Meng-Hsiang Chen, Nai-Wen Tsai, Chiun-Chieh Yu, Shieh-Yueh Yang, Cheng-Hsien Lu, Wei-Che Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
immunomagnetic reduction
plasma biomarker
plasma Aβ-40
Aβ-42
T-tau
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00112/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2020.00112/full

Similar Items