SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling

SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling

Abstract Background Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. SEMA4D is a 150 kDa transmembrane protein that belongs to the IV class of the subfamily of semaphorin family. Previous studies have reported that SEMA4D is a multifunctional target in many solid tum...

Full description

Bibliographic Details
Main Authors: Lu Liu, Lin Yang, Xiaojun Liu, Menghan Liu, Jing Liu, Xuefeng Feng, Ziyuan Nie, Jianmin Luo
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Translational Medicine
Subjects:
Acute myeloid leukemia
SEMA4D
PlexinB1
PI3K/Akt
Prognostic
Online Access:https://doi.org/10.1186/s12967-022-03500-w

Internet

https://doi.org/10.1186/s12967-022-03500-w

Similar Items