CCL2/CCR2 Axis Promotes the Progression of Salivary Adenoid Cystic Carcinoma via Recruiting and Reprogramming the Tumor-Associated Macrophages

CCL2/CCR2 Axis Promotes the Progression of Salivary Adenoid Cystic Carcinoma via Recruiting and Reprogramming the Tumor-Associated Macrophages

Objective: The present study investigated the roles and underlying mechanism of CCL2/CCR2 axis in the interactions between tumor cells and tumor-associated macrophages (TAMs) during the progression of salivary adenoid cystic carcinoma (SACC).Methods: Immunohistochemical staining and survival analysi...

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Bibliographic Details
Main Authors: Zihui Yang, Huan Li, Weiqi Wang, Jianying Zhang, Sen Jia, Jun Wang, Jianhua Wei, Delin Lei, Kaijin Hu, Xinjie Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
salivary adenoid cystic carcinoma (SACC)
tumor-associated macrophages (TAMs)
CCL2
CCR2
tumor progression
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00231/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00231/full

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