Thrombolytic therapy based on lyophilized platelet-derived nanocarriers for ischemic stroke

Abstract Background Intravenous administration of fibrinolytic drugs, such as recombinant tissue plasminogen activator (rtPA) is the standard treatment of acute thrombotic diseases. However, current fibrinolytics exhibit limited clinical efficacy because of their short plasma half-lives and risk of...

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Bibliographic Details
Main Authors: Martina Migliavacca, Clara Correa-Paz, María Pérez-Mato, Patrick-Brian Bielawski, Issan Zhang, Pauline Marie, Pablo Hervella, Marina Rubio, Dusica Maysinger, Denis Vivien, Pablo del Pino, Beatriz Pelaz, Ester Polo, Francisco Campos
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-023-02206-5