Integrated analysis of single-cell and bulk RNA sequencing data reveals an immunostimulatory microenvironment in tumor thrombus of osteosarcoma

Abstract Tumor thrombus of bone sarcomas represents a unique reservoir for various types of cancer and immune cells, however, the investigation of tumor thrombus at a single-cell level is very limited. And it is still an open question to identify the thrombus-specific tumor microenvironment that is...

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Bibliographic Details
Main Authors: Tao Ji, Qianyu Shi, Song Mei, Jiuhui Xu, Haijie Liang, Lu Xie, Tingting Ren, Kunkun Sun, Dasen Li, Xiaodong Tang, Peng Zhang, Wei Guo
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-023-00474-2