HETEROGENEITY OF EARLY RHEUMATOID ARTHRITIS PATIENTS ACCORDING TO BLOOD GENE EXPRESSION: THEORETICAL BASES OF A DIFFERENTIAL THERAPY APPROACH

Objective: to assess disease severity in relation to the expression of cell-division cycle genes: p21, a cyclin-dependent kinase inhibitor; caspase 3, an apoptotic activity indicator; mammalian target of rapamycin (mTOR), a major regulator of cell growth and proliferation; ATG1, a marker of autophag...

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Bibliographic Details
Main Authors: E V Chetina, N V Demidova, D E Karateev, E L Nasovov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2011-08-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/341