Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88

Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88

Abstract Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy o...

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Bibliographic Details
Main Authors: Takeshi Into, Toshi Horie, Megumi Inomata, Jin Gohda, Jun-ichiro Inoue, Yukitaka Murakami, Shumpei Niida
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01246-w

Internet

https://doi.org/10.1038/s41598-017-01246-w

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