Ivermectin contributes to attenuating the severity of acute lung injury in mice

Ivermectin contributes to attenuating the severity of acute lung injury in mice

Ivermectin has been proposed as a potential anti-inflammatory drug in addition to its antiparasitic activity. Here we investigated the potential role of ivermectin in the pathogenesis of acute lung injury (ALI) using the lipopolysaccharide (LPS)- or bleomycin (BLM)-induced mice models. Male C57BL/6...

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Bibliographic Details
Main Authors: Yuanqiao Ma, Xiaoxiao Xu, Hang Wu, Changbo Li, Peijie Zhong, Zejin Liu, Chuang Ma, Wenhua Liu, Chenyu Wang, Yijie Zhang, Junpeng Wang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ivermectin
ALI
Inflammation
MPO activity
MAPK signaling
NF-κB signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222010952

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http://www.sciencedirect.com/science/article/pii/S0753332222010952

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