Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models.

Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models.

Inverse statistical approaches to determine protein structure and function from Multiple Sequence Alignments (MSA) are emerging as powerful tools in computational biology. However the underlying assumptions of the relationship between the inferred effective Potts Hamiltonian and real protein structu...

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Bibliographic Details
Main Authors: Hugo Jacquin, Amy Gilson, Eugene Shakhnovich, Simona Cocco, Rémi Monasson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4866778?pdf=render

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http://europepmc.org/articles/PMC4866778?pdf=render

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