Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG

The molecular mechanisms underpinning the organization of microtubule arrays remain unclear. Here the authors show that in human cells, the microtubule polymerase ch-TOG promotes nucleation of microtubules at the interphase centrosome and the Golgi through a mechanism that involves transient interac...

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Bibliographic Details
Main Authors: Aamir Ali, Chithran Vineethakumari, Cristina Lacasa, Jens Lüders
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35955-w