Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3Research in context

Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3Research in context

Summary: Background: Tau is a microtubule-binding protein encoded by the MAPT gene. Tau is essential for several physiological functions and associated with pathological processes, including Alzheimer's disease (AD). Six tau isoforms are typically described in the central nervous system, but c...

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Bibliographic Details
Main Authors: Daniel Ruiz-Gabarre, Laura Vallés-Saiz, Almudena Carnero-Espejo, Isidro Ferrer, Félix Hernández, Ramon Garcia-Escudero, Jesús Ávila, Vega García-Escudero
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:EBioMedicine
Subjects:
Tau
Alzheimer's disease
Alternative splicing
Intron retention
Tau isoforms
Tauopathies
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423005194

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http://www.sciencedirect.com/science/article/pii/S2352396423005194

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