An expanded RT-PCR melting temperature coding assay to rapidly identify all known SARS-CoV-2 variants and sub-variants of concern

Abstract The continued emergence of vaccine-resistant SARS-CoV-2 variants of concern (VOC) requires specific identification of each VOC as it arises. Here, we report an expanded version of our previously described sloppy molecular beacon (SMB) melting temperature (Tm) signature-based assay for VOCs,...

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Bibliographic Details
Main Authors: Padmapriya P. Banada, Raquel Green, Deanna Streck, Rohini Kurvathi, Robert Reiss, Sukalyani Banik, Naranjargal Daivaa, Ibsen Montalvan, Robert Jones, Salvatore A. E. Marras, Soumitesh Chakravorty, David Alland
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48647-8