Repair of bone defects in rhesus monkeys with α1,3-galactosyltransferase-knockout pig cancellous bone

Repair of bone defects in rhesus monkeys with α1,3-galactosyltransferase-knockout pig cancellous bone

Introduction: Since xenografts offer a wide range of incomparable advantages, they can be a better option than allografts but only if the possibility of immunological rejection can be eliminated. In this study, we investigated the ability of α1,3-galactosyltransferase (α1,3-GT) gene knockout (GTKO)...

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Main Authors: Wenhao Wang, Jiansen Lu, Ying Song, Chun Zeng, Yongkui Wang, Cheng Yang, Bin Huang, Yifan Dai, Jian Yang, Liangxue Lai, Liping Wang, Daozhang Cai, Xiaochun Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cylindrical bone defect
gene knockout pig
xenotransplantation
bone transplantation
repair
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.990769/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.990769/full

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