The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains

N-linked glycosylation of the fragment crystallizable (Fc)-region of immunoglobulin G (IgG) is known to have a large influence on the activity of the antibody, an effect reported to be IgG subclass specific. This situation applies both to humans and mice. The mouse is often used as experimental anim...

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Главные авторы: Noortje de Haan, Karli R. Reiding, Jasminka Krištić, Agnes L. Hipgrave Ederveen, Gordan Lauc, Manfred Wuhrer
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2017-05-01
Серии:Frontiers in Immunology
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Online-ссылка:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00608/full