Red blood cells and their releasates compromise bone marrow-derived human mesenchymal stem/stromal cell survival in vitro

Red blood cells and their releasates compromise bone marrow-derived human mesenchymal stem/stromal cell survival in vitro

Abstract Purpose The use of bone marrow aspirate (BMA) and bone marrow aspirate concentrate (BMC) in the treatment of inflammatory orthopedic conditions has become a common practice. The therapeutic effect of BMA/BMC is thought to revolve primarily around the mesenchymal stem/stromal cell (MSC) popu...

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Bibliographic Details
Main Authors: Ryan Christopher Dregalla, Jessica Ann Herrera, Edward Jeffery Donner
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Bone marrow aspirate concentrate
Hematocrit
Red blood cells
Viability
Apoptosis
Online Access:https://doi.org/10.1186/s13287-021-02610-4

Internet

https://doi.org/10.1186/s13287-021-02610-4

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