An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection

An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection

Abstract Zika virus (ZIKV), an arbovirus transmitted by mosquitoes, was identified as a cause of congenital disease during a major outbreak in the Americas in 2016. Vaccine design strategies relied on limited available isolate sequence information due to the rapid response necessary. The first-gener...

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Bibliographic Details
Main Authors: Brooke Bollman, Naveen Nunna, Kapil Bahl, Chiaowen Joyce Hsiao, Hamilton Bennett, Scott Butler, Bryant Foreman, Katherine E. Burgomaster, Maya Aleshnick, Wing-Pui Kong, Brian E. Fisher, Tracy J. Ruckwardt, Kaitlyn M. Morabito, Barney S. Graham, Kimberly A. Dowd, Theodore C. Pierson, Andrea Carfi
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00656-4

Internet

https://doi.org/10.1038/s41541-023-00656-4

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