DREADD activation of the lateral orbitofrontal increases cocaine-taking and cocaine-seeking in male and female rats during intermittent access self-administration under risky conditions
Addiction is a disorder that can be characterized in part as the constant pursuit of a particular substance despite negative consequences. Although the orbitofrontal cortex (OFC) is known to regulate risk-taking more generally and be critical to the development of addiction, its role in regulating d...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Addiction Neuroscience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772392523000652 |