Chronic radiation-associated dysphagia in oropharyngeal cancer survivors: Towards age-adjusted dose constraints for deglutitive muscles

Objectives: We sought to model chronic radiation-associated dysphagia (RAD) in patients given intensity-modulated radiation therapy (IMRT) for oropharyngeal squamous cell cancer (OPSCC) as a function of age and dose to non-target swallowing muscles. Methods: We reviewed 300 patients with T1-T4 N0-3 ...

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Main Authors: Kaitlin M. Christopherson, Alokananda Ghosh, Abdallah Sherif Radwan Mohamed, Mona Kamal, G. Brandon Gunn, Timothy Dale, Jayashree Kalpathy-Cramer, Jay Messer, Adam S. Garden, Hesham Elhalawani, Steven J. Frank, Jan Lewin, William H. Morrison, Jack Phan, Neil Gross, Renata Ferrarotto, Randal S. Weber, David I. Rosenthal, Stephen Y. Lai, Katherine Hutcheson, Clifton David Fuller, G. Elisabeta (Liz) Marai, Guadalupe Canahuate, David M. Vock, David Fuller
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630819300813