An association of CSF apolipoprotein E glycosylation and amyloid-beta 42 in individuals who carry the APOE4 allele

An association of CSF apolipoprotein E glycosylation and amyloid-beta 42 in individuals who carry the APOE4 allele

Abstract Carrying the apolipoprotein E (ApoE) Ɛ4 allele is associated with an increased risk of cerebral amyloidosis and late-onset Alzheimer’s disease, but the degree to which apoE glycosylation affects its development is not clear. In a previous pilot study, we identified distinct total and second...

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Bibliographic Details
Main Authors: Cristiana J. Meuret, Yueming Hu, Sabrina Smadi, Mikaila Ann Bantugan, Haotian Xian, Ashley E. Martinez, Ronald M. Krauss, Qiu-Lan Ma, Dobrin Nedelkov, Hussein N. Yassine
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Alzheimer’s Research & Therapy
Subjects:
Apolipoprotein E
Isoform
Glycan
Mass spectrometry
Alzheimer’s disease
Online Access:https://doi.org/10.1186/s13195-023-01239-0

Internet

https://doi.org/10.1186/s13195-023-01239-0

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