Bacteriophage-resistant mutants in Yersinia pestis: identification of phage receptors and attenuation for mice.

Bacteriophage-resistant mutants in Yersinia pestis: identification of phage receptors and attenuation for mice.

BACKGROUND: Bacteriophages specific for Yersinia pestis are routinely used for plague diagnostics and could be an alternative to antibiotics in case of drug-resistant plague. A major concern of bacteriophage therapy is the emergence of phage-resistant mutants. The use of phage cocktails can overcome...

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Bibliographic Details
Main Authors: Andrey A Filippov, Kirill V Sergueev, Yunxiu He, Xiao-Zhe Huang, Bryan T Gnade, Allen J Mueller, Carmen M Fernandez-Prada, Mikeljon P Nikolich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182234?pdf=render

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http://europepmc.org/articles/PMC3182234?pdf=render

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