Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells

Purpose Hypoxia-mediated neurotoxicity contributes to various neurodegenerative disorders, including Alzheimer disease. Neuregulin-1 (NRG1) plays an important role in the development and plasticity of the brain. The aim of the present study was to investigate the neuroprotective effect and the regul...

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Bibliographic Details
Main Authors: Seung-Yeon Yoo, Ji-Young Yoo, Han-Byeol Kim, Tai-Kyoung Baik, Jun-Ho Lee, Ran-Sook Woo
Format: Article
Language:English
Published: Korean Continence Society 2019-11-01
Series:International Neurourology Journal
Subjects:
Online Access:http://www.einj.org/upload/pdf/inj-1938190-095.pdf