Formation of the long range Dpp morphogen gradient.
The TGF-β homolog Decapentaplegic (Dpp) acts as a secreted morphogen in the Drosophila wing disc, and spreads through the target tissue in order to form a long range concentration gradient. Despite extensive studies, the mechanism by which the Dpp gradient is formed remains controversial. Two opposi...
Principais autores: | , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2011-07-01
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coleção: | PLoS Biology |
Acesso em linha: | https://doi.org/10.1371/journal.pbio.100111 |