Peripheral immune cell death in sepsis based on bulk RNA and single-cell RNA sequencing

Peripheral immune cell death in sepsis based on bulk RNA and single-cell RNA sequencing

Background: Immune cell activation in early sepsis is beneficial to clear pathogens, but immune cell exhaustion during the inflammatory response induces immunosuppression in sepsis. Here, we studied the relationship between immune cell survival status and the prognosis of sepsis patients. Methods: S...

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Bibliographic Details
Main Authors: Shanshou Liu, Chujun Duan, Jiangang Xie, Jinxin Zhang, Xu Luo, Qianmei Wang, Xiaoli Liang, Xiaojun Zhao, Ran Zhuang, Wei Zhao, Wen Yin
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Sepsis
Immune cells
PBMC
Single-cell RNA sequencing
Cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023049721

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http://www.sciencedirect.com/science/article/pii/S2405844023049721

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