Substrate Promiscuity of N-Acetylhexosamine 1-Kinases

Substrate Promiscuity of N-Acetylhexosamine 1-Kinases

N-Acetylhexosamine 1-kinase (NahK) catalyzes the direct addition of a phosphate from adenosine 5'-triphosphate (ATP) to the anomeric position of N-acetylhexosamine and shows similar activity towards N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc). Herein we report the cloning, c...

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Bibliographic Details
Main Authors: Hongzhi Cao, Li Cai, Xi Chen, Peng George Wang, Vinod Kumar Tiwari, Jingyao Qu, Vireak Thon, Kam Lau, Yi Chen, Hai Yu, Yanhong Li
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Molecules
Subjects:
N-acetylgalactosamine
N-acetylglucosamine
N-acetylhexosamine 1-kinase
mannose
substrate specificity
Online Access:http://www.mdpi.com/1420-3049/16/8/6396/

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http://www.mdpi.com/1420-3049/16/8/6396/

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