Topiramate Inhibits Capsaicin-Induced Mast Cell Degranulation and CGRP Release in Rat Dura Mater

Topiramate Inhibits Capsaicin-Induced Mast Cell Degranulation and CGRP Release in Rat Dura Mater

Background/Objectives: Migraine is a disease that stands out for its high prevalence and socioeconomic costs. It involves the entire trigeminovascular system, the signaling substances, and their targets. However, the role of meningeal mast cells in migraine is still unclear. To better understand one...

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Bibliographic Details
Main Authors: Raisa Ferreira Costa, Emanuela Paz Rosas, Silvania Tavares Paz, Manuela Figueiroa Lyra de Freitas, Sandra Lopes de Souza, Juliana Ramos de Andrade, Daniella Araújo de Oliveira, Inger Jansen-Olesen, Sarah Louise Christensen, Marcelo Moraes Valença
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Brain Sciences
Subjects:
migraine
pathophysiology
CGRP
endogenous substances
mast cells
animal model
Online Access:https://www.mdpi.com/2076-3425/14/11/1070

Internet

https://www.mdpi.com/2076-3425/14/11/1070

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