Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

Anti-neutrophil cytoplasmic autoantibodies (ANCA) targeting proteinase 3 (PR3) and myeloperoxidase expressed by innate immune cells (neutrophils and monocytes) are salient diagnostic and pathogenic features of small vessel vasculitis, comprising granulomatosis with polyangiitis (GPA), microscopic po...

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Bibliographic Details
Main Authors: Peter Lamprecht, Anja Kerstein, Sebastian Klapa, Susanne Schinke, Christian M. Karsten, Xinhua Yu, Marc Ehlers, Jörg T. Epplen, Konstanze Holl-Ulrich, Thorsten Wiech, Kathrin Kalies, Tanja Lange, Martin Laudien, Tamas Laskay, Timo Gemoll, Udo Schumacher, Sebastian Ullrich, Hauke Busch, Saleh Ibrahim, Nicole Fischer, Katrin Hasselbacher, Ralph Pries, Frank Petersen, Gesche Weppner, Rudolf Manz, Jens Y. Humrich, Relana Nieberding, Gabriela Riemekasten, Antje Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
anti-neutrophil cytoplasmic autoantibodies
anti-neutrophil cytoplasmic autoantibody vasculitides
microscopic polyangiitis
granulomatosis with polyangiitis
eosinophilic granulomatosis with polyangiitis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00680/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00680/full

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