Design, Synthesis, and Biological Evaluation of PKD Inhibitors

Design, Synthesis, and Biological Evaluation of PKD Inhibitors

Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PKD has been limited due to the lack of a PKD-specif...

Full description

Bibliographic Details
Main Authors: Marie-Céline Frantz, Karla Bravo-Altamirano, Courtney R. LaValle, Manuj Tandon, Stephanie Leimgruber, Elizabeth R. Sharlow, John S. Lazo, Q. Jane Wang, Peter Wipf, Kara M. George
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Pharmaceutics
Subjects:
protein kinase D
small molecule inhibitor
benzothienothiazepinone
pyrimidines
CID755673
thiazepinothiophenopyrimidinone
Online Access:http://www.mdpi.com/1999-4923/3/2/186/

Internet

http://www.mdpi.com/1999-4923/3/2/186/

Similar Items