Nobiletin, a NF‐κB signaling antagonist, promotes BMP‐induced bone formation

Nobiletin, a NF‐κB signaling antagonist, promotes BMP‐induced bone formation

Abstract The NF‐κB family of transcription factors plays an important role in skeletal development and bone homeostasis. In osteoblast cells, NF‐κB signaling has been shown to suppress survival, proliferation, and differentiation. Furthermore, pharmacological suppression of NF‐κB enhances osteoblast...

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Bibliographic Details
Main Authors: Thira Rojasawasthien, Michihiko Usui, William N. Addison, Takuma Matsubara, Tomohiko Shirakawa, Toshiyuki Tsujisawa, Keisuke Nakashima, Shoichiro Kokabu
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:FASEB BioAdvances
Subjects:
BMPs
bone formation
NF‐κB signaling
Nobiletin
TNF‐α
Online Access:https://doi.org/10.1096/fba.2022-00093

Internet

https://doi.org/10.1096/fba.2022-00093

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