Can Dexrazoxane and Carvedilol prevent Doxorubicin-induced nephrotoxicity?

Doxorubicin (DOX) is a cytostatic drug with a broad spectrum of anticancer activity that has been used in oncology for over 50 years. Among many adverse effects in humans, the most dangerous is late dilated cardiomyopathy, which appears even years after completion of therapy. However, in cats, the c...

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Bibliographic Details
Main Authors: Szponar Jaroslaw, Gorska Agnieszka, Ostrowska-Lesko Marta, Wielgomas Bartosz, Mandziuk Slawomir
Format: Article
Language:English
Published: Sciendo 2024-12-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:https://doi.org/10.2478/cipms-2024-0038