Design and Synthesis of Novel Dehydroepiandrosterone Analogues as Potent Antiproliferative Agents

The aim of the present study was to determine the cytotoxic effects of a series of novel dehydroepiandrosterone derivatives containing triazole at the C16 position on human cancer cells. The cancer cells used in the present study were A549, Hela, HepG-2, BEL7402, MCF-7, and HCT116. Several of the sy...

Full description

Bibliographic Details
Main Authors: Xing Huang, Qing-Kun Shen, Hong-Jian Zhang, Jia-Li Li, Yu-Shun Tian, Zhe-Shan Quan
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/9/2243