Regulation of Oncogenic Targets by the Tumor-Suppressive <i>miR-139</i> Duplex (<i>miR-139-5p</i> and <i>miR-139-3p</i>) in Renal Cell Carcinoma

Regulation of Oncogenic Targets by the Tumor-Suppressive <i>miR-139</i> Duplex (<i>miR-139-5p</i> and <i>miR-139-3p</i>) in Renal Cell Carcinoma

We previously found that both the guide and passenger strands of the <i>miR-139</i> duplex (<i>miR-139-5p</i> and <i>miR-139-3p</i>, respectively) were downregulated in cancer tissues. Analysis of TCGA datasets revealed that low expression of <i>miR-139-5p&l...

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Bibliographic Details
Main Authors: Reona Okada, Yusuke Goto, Yasutaka Yamada, Mayuko Kato, Shunichi Asai, Shogo Moriya, Tomohiko Ichikawa, Naohiko Seki
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
<i>miR-139-5p</i>
<i>miR-139-3p</i>
renal cell carcinoma (RCC)
microRNA
tumor suppressor
paxillin (<i>PXN</i>)
Online Access:https://www.mdpi.com/2227-9059/8/12/599

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https://www.mdpi.com/2227-9059/8/12/599

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