A Third Dose of an Inactivated Vaccine Dramatically Increased the Levels and Decay Times of Anti-SARS-CoV-2 Antibodies, but Disappointingly Declined Again: A Prospective, Longitudinal, Cohort Study at 18 Serial Time Points Over 368 Days

A Third Dose of an Inactivated Vaccine Dramatically Increased the Levels and Decay Times of Anti-SARS-CoV-2 Antibodies, but Disappointingly Declined Again: A Prospective, Longitudinal, Cohort Study at 18 Serial Time Points Over 368 Days

BackgroundDue to anti-SARS-CoV-2 antibody decay and SARS-CoV-2 variants, vaccine booster doses are a constant concern. It was focused on whether the third dose can quickly evoke and activate immunity and produce a sufficient and durable immune protection.ObjectivesTo evaluate the responses and durat...

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Bibliographic Details
Main Authors: Xian-Ming Liang, Qiu-Yan Xu, Zhi-Juan Jia, Meng-Juan Wu, Yan-Yun Liu, Li-Rong Lin, Li-Li Liu, Tian-Ci Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
neutralizing antibody
anti-SARS-CoV-2 antibody
CoronaVac
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.876037/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.876037/full

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