Surface Functionalization of Calcium Phosphate Nanoparticles via Click Chemistry: Covalent Attachment of Proteins and Ultrasmall Gold Nanoparticles

Surface Functionalization of Calcium Phosphate Nanoparticles via Click Chemistry: Covalent Attachment of Proteins and Ultrasmall Gold Nanoparticles

Calcium phosphate nanoparticles (60 nm) were stabilized with either polyethyleneimine (PEI; polycationic electrolyte) or carboxymethylcellulose (CMC; polyanionic electrolyte). Next, a silica shell was added and terminated with either azide or alkyne groups via siloxane coupling chemistry. The partic...

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Bibliographic Details
Main Authors: Kathrin Kostka, Matthias Epple
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Chemistry
Subjects:
calcium phosphate
nanoparticles
surface functionalization
proteins
drug delivery
click chemistry
Online Access:https://www.mdpi.com/2624-8549/5/2/72

Internet

https://www.mdpi.com/2624-8549/5/2/72

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