Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients

Abstract Background In Head and neck cancer (HNC) angiogenesis is essential for tumor progression and metastasis. Small extracellular vesicles (sEVs) from HNC cell lines alter endothelial cell (EC) functions towards a pro-angiogenic phenotype. However, the role of plasma sEVs retrieved from HNC pati...

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Main Authors: Luisa Tengler, Julia Schütz, Moritz Tiedtke, Jadwiga Jablonska, Marie-Nicole Theodoraki, Katja Nitschke, Christel Weiß, Elena Seiz, Annette Affolter, Frederic Jungbauer, Anne Lammert, Nicole Rotter, Sonja Ludwig
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-023-00659-w