Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich’s ataxia mouse model

Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich’s ataxia mouse model

Summary: Friedreich’s ataxia (FA) is a neurodegenerative disease resulting from a mutation in the FXN gene, leading to mitochondrial frataxin deficiency. FA patients exhibit increased visceral adiposity, inflammation, and heightened diabetes risk, negatively affecting prognosis. We investigated visc...

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Bibliographic Details
Main Authors: Riccardo Turchi, Francesca Sciarretta, Veronica Ceci, Marta Tiberi, Matteo Audano, Silvia Pedretti, Concetta Panebianco, Valentina Nesci, Valerio Pazienza, Alberto Ferri, Simone Carotti, Valerio Chiurchiù, Nico Mitro, Daniele Lettieri-Barbato, Katia Aquilano
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Pharmacology
Natural sciences
Biological sciences
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301790X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422301790X

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