Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure

Viral capsids need to protect the genome against harsh environmental conditions and cope with high internal pressure from the packaged genome. Here, the authors determine the structure of the thermostable phage P74-26 capsid at 2.8-Å resolution and identify features underlying enhanced capsid capaci...

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Bibliographic Details
Main Authors: Nicholas P. Stone, Gabriel Demo, Emily Agnello, Brian A. Kelch
Format: Article
Language:English
Published: Nature Portfolio 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12341-z