Regulation of MRTF-A by JMY via a nucleation-independent mechanism

Regulation of MRTF-A by JMY via a nucleation-independent mechanism

Abstract Background MRTF-A (myocardin-related transcription factor A) is a coactivator for SRF-mediated gene expression. The activity of MRTF-A is critically dependent on the dissociation of G-actin from N-terminal RPEL motifs. MRTF-SRF induction often correlates with enhanced polymerization of F-ac...

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Bibliographic Details
Main Authors: Franziska Kluge, Julia Weissbach, Anja Weber, Theresia Stradal, Guido Posern
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cell Communication and Signaling
Subjects:
Mrtf
Actin
Transcription
WH2 domains
JMY
Nucleators
Online Access:http://link.springer.com/article/10.1186/s12964-018-0299-x

Internet

http://link.springer.com/article/10.1186/s12964-018-0299-x

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