Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum

<p>Abstract</p> <p>Background</p> <p>CD72 is an inhibitory co-receptor expressed on B cells. We previously demonstrated significant association of the polymorphism of the <it>CD72</it> gene with susceptibility to human systemic lupus erythematosus (SLE) in i...

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Bibliographic Details
Main Authors: Hitomi Yuki, Adachi Takahiro, Tsuchiya Naoyuki, Honda Zen-Ichiro, Tokunaga Katsushi, Tsubata Takeshi
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Immunology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2172/13/72